Report: Uruguay 1-0 Paraguay
In Monday's other Group A game, Uruguay clinched second place in the table after downing Paraguay 1-0 in Rio de Janeiro.
Edinson Cavani's first half spot kick proved decisive for 'La Celeste', sending Uruguay into a quarter-final against Colombia on Saturday.
Paraguay finished third and will now play Peru on Friday. Chile, who finished fourth in Group A, face a daunting task against hosts Brazil on Friday.