Rangers faces a two-legged tie against Jose Mourinho's Fenerbahce next month, with all three British teams at home in the second leg.

United or Real Sociedad will then play FCSB or Lyon in the final eight.

Ruben Amorim has a 100 per cent record with his new side in the competition, overseeing four wins from four in the league stage.

The winner of the tie between AZ and Tottenham will play the winner of Eintracht Frankfurt v Ajax in the quarter-finals, meaning Spurs could potentially face a rematch of their famous 2019 UEFA Champions League semi-final victory over the Dutch giant.

Elsewhere, Bodo/Glimt has been drawn to play Olympiakos, while Viktoria Plzen was pulled out to face Lazio.

Roma will take on Athletic Bilbao in the Round of 16, with ties set to be played on 7 March and 14 March AEDT.

UEFA EUROPA ROUND OF 16 DRAW

Bodo/Glimt v Olympiakos

Fenerbahce v Rangers

Ajax v Eintracht Frankfurt

FCSB v Lyon

AZ v Tottenham

Real Sociedad v Manchester United

Viktoria Plzen v Lazio

Roma v Athletic Club