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The 26 year-old’s powerful and precise groundstrokes proved too much even for the retrieval skills of Medvedev, who dropped serve in seven of his eight service games.

“We’ve played each other many times and played each other on basically every surface,” De Minaur said. “I tried to draw a lot on our last match at Roland Garros [in 2024] and see what worked for me. I thought I executed really well… I thought I was smart and tactically played the right way today.”

De Minaur has done plenty of winning in 2025 - he has notched a Tour-leading 19 victories this year - but this was his first triumph against a Top 20 opponent in 10 attempts dating back to last October. Yet there was no lack of confidence in the way the Australian powered past Medvedev in 72 minutes.

“More than anything, I’m just finding my feet on clay,” De Minaur said. “It’s taken me a while in my career, but I finally understand what I need to do to be effective on this surface. 

"I can be dangerous on this surface, so I’m very happy to play here and start off the clay swing with some good matches. All my energy and all my effort now goes to tomorrow.”

De Minaur will play 15th seed Grigor Dimitrov in the last eight on Friday after the Bulgarian defeated Novak Djokovic-conqueror Alejandro Tabilo 6-3, 3-6, 6-2. 

De Minaur is just the third Australian to reach multiple Monte-Carlo quarter-finals in the Open Era, after Dick Crealy and John Alexander.

Despite his third-round defeat, Medvedev could still return to the Top 10 in the ATP Rankings after Monte-Carlo. He is up two spots to No. 9 in the ATP Live Rankings, but four players still alive in the draw could yet overtake him this week.

De Minaur's countryman, Alexei Popyrin, is also through to the last eight in Monte Carlo after a stunning 6-4 3-6 7-5 win over Casper Ruud. 

The 25 year-old will face Spaniard Alejandro Davidovich Fokina for a plce in the final four.